Treatment of pml targeting jc virus agno

Details Treatment of pml targeting jc virus agno Treatment of pml targeting jc virus agno

C - Chemistry, Metallurgy

12

N

C12N 7/04 (2006.01) A61K 39/395 (2006.01) A61K 45/00 (2006.01) A61K 48/00 (2006.01) A61P 31/20 (2006.01) A61P 43/00 (2006.01) C07K 14/025 (2006.01) C07K 16/08 (2006.01) C12N 15/09 (2006.01) C12P 21/08 (2006.01)

Patent

CA 2467930

It is intended to provide an effective method of treating PML (human progressive multifocal leukoencephalopathy). A method of inhibiting the proliferation of JC virus in JC virus-infected cells by inhibiting the expression of JV virus agno gene; and a method of inhibiting the canceration of JC virus-infected cells.

Cette invention se rapporte à un procédé efficace pour traiter la leucoencéphalopathie multifocale progressive (LEMP) chez l'homme. A cet effet, on utilise un procédé qui inhibe la prolifération du virus JC dans les cellules infectées par le virus JC, en inhibant l'expression du gène agno du virus JC; et un procédé qui inhibe la cancérisation des cellules infectées par le virus JC.

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