Treatment of postmenopausal disorders

A - Human Necessities – 61 – K

Patent

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167/191

A61K 31/56 (2006.01) A61K 31/565 (2006.01) A61K 31/57 (2006.01)

Patent

CA 2018818

A method is provided for the treatment of postmenopausal disorders which comprises administering to a woman in single, oral, daily dose form during an uninterrupted consecutive sequence of 90 days, (a) a daily, oral, dose in an uninterrupted consecutive sequence for 69 days starting on the first day of a naturally occurring or synthetic estrogenic compound effective in the prevention of climacteric symptoms; (b) a daily, oral dose in an uninterrupted consecutive sequence from the 70th day to the 83rd day following said first day, of a naturally occurring or synthetic estrogenic compound and a compound having progestational activity effective in preventing the development of endometrial hyperplasia; and optionally (c) a daily, oral dose in an uninterrupted consecutive sequence from the 84th to the 90th day following said first day, of a compound free of estrogen and progestogen.

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