Treatment of prostatic carcinoma with 17beta-n-mono-...

Details Treatment of prostatic carcinoma with 17beta-n-mono-... Treatment of prostatic carcinoma with 17beta-n-mono-...

A - Human Necessities

61

K

167/227

A61K 31/56 (2006.01) A61K 31/58 (2006.01)

Patent

CA 1302276

ABSTRACT OF THE INVENTION 17.beta.-N-monosubstituted-carbamoyl-4-aza-5.alpha.- androst-1-en-3-ones of the formula: Image wherein R1 is selected from hydrogen, methyl and ethyl and R2 is a branched chain alkyl of from 3-12 carbons, and R', R" and R"' are hydrogen or methyl are active as testosterone 5.alpha.- reductase inhibitors and are useful for the treatment of prostatic car- cinoma.

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