A - Human Necessities – 61 – K
Patent
A - Human Necessities
61
K
A61K 9/14 (2006.01) A61K 33/00 (2006.01) A61K 33/42 (2006.01) A61M 15/00 (2006.01)
Patent
CA 2203118
Methods and compositions for the treatment of the symptoms of a patient who has a pulmonary condition associated with an inhibition of surfactant secretion by type II alveolar cells are described. The method of treatment involves causing a patient to inhale an amount of a pH-raising buffer effective to raise the pH of the aqueous fluid in the microenvironment of the type II alveolar cell lumenal surface, thereby inducing an increase in the rate of surfactant secretion by type II alveolar cells.
Méthodes et compositions pour le traitement de symptômes chez un patient présentant des troubles pulmonaires associées à une inhibition de la sécrétion de tensioactifs par les cellules alvéolaires de type II. La méthode consiste à faire inhaler au patient une dose efficace d'un tampon élevant le pH du fluide aqueux du microenvironement de la surface luminale des cellules alvéolaires de type II, ce qui a pour effet d'accroître le taux de sécrétion de tensioactifs par les cellules alvéolaires de type II.
Alphagene Inc.
Kirby Eades Gale Baker
Scheele George
LandOfFree
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