Treatment of pulmonary hypertension

Details Treatment of pulmonary hypertension Treatment of pulmonary hypertension

A - Human Necessities

61

K

A61K 31/135 (2006.01) A61K 31/137 (2006.01)

Patent

CA 2366652

A compound of formula (I) or a pharmaceutically acceptable salt thereof in which R1 and R2 are independently H or methyl (for example N,N-dimethyl-1-[1- (4chlorophenyl)cyclobutyl]-3-methylbutyl amine hydrochloride optionally in the form of its monohydrate) is used for treating pulmonary hypertension, particularly in patients who take certain anorectic medications.

L'invention concerne un composé correspondant à la formule (I), ou un sel de celui-ci, acceptable sur le plan pharmacologique. Dans cette formule R¿1? et R¿2? représentent indépendamment H ou méthyle (par exemple du chlorhydrate de N, N-diméthyl-1-¢1-(4chlorophényl)cyclobutyl]-3-méthylbutylamine, éventuellement sous la forme de son monohydrate). Ce composé est utile dans le traitement de l'hypertension artérielle pulmonaire, notamment chez des patients soumis à une certaine médication anorexiante.

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