Treatment of renal carcinoma using antibodies against the egfr

Details Treatment of renal carcinoma using antibodies against the egfr Treatment of renal carcinoma using antibodies against the egfr

A - Human Necessities

61

K

A61K 39/395 (2006.01) C07K 16/28 (2006.01)

Patent

CA 2485691

Methods of treating renal carcinoma are described using fully human monoclonal antibodies ABX-EGF against the epidermal growth factor receptor (EGFr) and antigen binding fragments thereof. Methods of using these renal carcinoma treatments specifically as a monotherapy are also described. In addition, a kit and an article of manufacture for the treatment of renal carcinoma treatment are provided.

L'invention concerne des méthodes de traitement du carcinome rénal, utilisant des anticorps monoclonaux entièrement humains ABX-EGF dirigés contre le récepteur du facteur de croissance épidermique (EGFR) et des fragments de reconnaissance de l'antigène de ces anticorps. L'invention concerne également des méthodes d'administration de ce traitement, principalement en monothérapie. L'invention concerne également un nécessaire et un article de fabrication destinés au traitement du carcinome rénal.

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