A - Human Necessities – 61 – K
Patent
A - Human Necessities
61
K
A61K 31/10 (2006.01) A61P 3/04 (2006.01) A61P 3/06 (2006.01) A61P 9/10 (2006.01) A61P 9/12 (2006.01) A61P 13/10 (2006.01)
Patent
CA 2634871
Disclosed herein are methods, compounds and compositions for preventing or treating a renal disorder or chronic kidney diseases, including nephropathies such as diabetic nephropathy. The invention generally includes administering to a subject 1,3-propanedisulfonic acid or a pharmaceutically acceptable salt thereof, e.g., 1,3- propanedisulfonic acid sodium salt. The invention also relates to methods, compounds and compositions for the prevention and/or treatment of for preventing or treating a renal disorder complication. The invention further relates to methods, compounds and compositions for the prevention and/or treatment of dyslipidemia, and more particularly for reducing levels of harmful serum lipid levels, especially cholesterol and triglycerides in diabetic patients.
L'invention concerne des procédés, des composés et des compositions destinés à la prévention ou au traitement d'un trouble rénal ou de maladies rénales chroniques, y compris des néphropathies telles que la néphropathie diabétique. De manière générale, l'invention comprend l'administration à un sujet d'acide 1,3-propanedisulfonique ou d'un de ses sels pharmaceutiquement acceptables, par exemple le 1,3-propanedisulfonate de sodium. L'invention concerne également des procédés, des composés et des compositions destinés à la prévention et/ou au traitement d'une complication d'un trouble rénal. L'invention concerne en outre des procédés, des composés et des compositions destinés à la prévention et/ou au traitement de la dyslipidémie et plus particulièrement à la réduction des taux de lipides sériques nocifs, notamment le cholestérol et les triglycérides chez les patients diabétiques.
Hamet Pavel
Hauck Wendy
Bellus Health (international) Limited
Gowling Lafleur Henderson Llp
Neurochem (international) Limited
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