C - Chemistry – Metallurgy – 12 – N
Patent
C - Chemistry, Metallurgy
12
N
C12N 15/113 (2010.01) A61K 31/713 (2006.01) A61K 48/00 (2006.01) C12N 15/63 (2006.01) C12Q 1/68 (2006.01)
Patent
CA 2762369
The present invention relates to antisense oligonucleotides that modulate the expression of and/or function of a Reprogramming factor, in particular, by targeting natural antisense polynucleotides of a Reprogramming factor. The invention also relates to the identification of these antisense oligonucleotides and their use in treating diseases and disorders associated with the expression of Reprogramming factors.
Cette invention concerne des oligonucléotides antisens modulant l'expression et/ou la fonction d'un facteur de reprogrammation, en particulier, en ciblant les polynucléotides antisens naturels d'un facteur de reprogrammation. L'invention concerne également l'identification de ces oligonucléotides antisens et leur utilisation dans le traitement des maladies et des affections associées à l'expression de facteurs de reprogrammation.
Collard Joseph
Khorkova Sherman Olga
Norton Rose Canada S.e.n.c.r.l.,s.r.l./llp
Opko Curna Llc
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