Treatment of respiratory diseases

A - Human Necessities – 61 – K

Patent

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Details

A61K 33/00 (2006.01) A61K 31/02 (2006.01) A61K 31/131 (2006.01) A61K 31/137 (2006.01) A61K 31/352 (2006.01)

Patent

CA 2633099

A method for treating a mammal suffering from a respiratory disease characterized by acute intermittent or chronic obstruction of the airways of the lungs, such as asthma, acute asthma, chronic obstructive pulmonary disease (COPD) and bronchiectasis comprising delivering to the lungs of the mammal a perfluorocarbon and a gas mixture comprising carbon dioxide (CO2), and pharmaceutical compositions of CO2 and perfluorocarbons are provided. The acute relief of airway obstruction provided by the said treatment provides an opportunity for concomitant or subsequent delivery of additional suitable active agent of conventional treatments.

L~invention concerne une méthode pour traiter un mammifère qui souffre d'une maladie respiratoire caractérisée par une obstruction aiguë, intermittente ou chronique des voies respiratoires pulmonaires, telle que de l'asthme, de l~asthme aigu, la bronchopneumopathie chronique obstructive (BPCO) et une bronchiectasie, qui consiste à livrer aux poumons d~un mammifère un perfluorocarbone et un mélange de gaz comprenant du dioxyde de carbone (CO2), et des compositions pharmaceutiques de CO2 et de perfluorocarbones. Le soulagement aigu d'une obstruction des voies respiratoires obtenu par ledit traitement permet une livraison concomitante ou subséquente d'un agent actif approprié supplémentaire associé aux traitements conventionnels.

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