Treatment of rheumatoid arthritis

A - Human Necessities – 61 – K

Patent

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Details

A61K 48/00 (2006.01) A61K 31/105 (2006.01) A61K 31/7088 (2006.01) A61K 31/711 (2006.01) A61K 31/713 (2006.01) A61P 19/02 (2006.01)

Patent

CA 2692287

The present invention provides a method for treating or inhibiting rheumatoid arthritis in a subject, the method comprising administering to the subject a therapeutically effective amount of a nucleic acid which decreases the level of c-Jun mRNA, c-Jun mRNA translation or nuclear accumulation or activity of c-Jun protein.

La présente invention porte sur un procédé pour traiter ou inhiber la polyarthrite rhumatoïde chez un sujet, le procédé comprenant l'administration au sujet d'une quantité thérapeutiquement efficace d'un acide nucléique qui diminue le taux d'ARNm c-Jun, la traduction de l'ARNm c-Jun ou l'accumulation ou l'activité nucléaire de la protéine c-Jun.

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