Treatment of rheumatoid arthritis using imatinib

A - Human Necessities – 61 – K

Patent

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Details

A61K 31/506 (2006.01) A61K 31/573 (2006.01) A61K 45/06 (2006.01)

Patent

CA 2473158

4-(4-methylpiperazin-1-ylmethyl)-N-[4-methyl-3-(4-pyridin-3-yl)pyrimidin-2- ylamino)phenyl]-benzamide of the formula (I), or a pharmaceutically acceptable salt thereof can be used in the treatment of rheumatoid arthritis. The invention also relates to a combination of the compound of the formula I or a pharmaceutically acceptable salt thereof with one or more disease modifying arthritis rheumatoid drugs (DMARDs).

Il est possible d'utiliser 4-(4-méthylpipérazin-1-ylméthyl)-N-[4-méthyl-3-(4-pyridin-3-yl)pyrimidin-2-ylamino)phényl]-benzamide correspondant à la formule (I) ou un sel de cette substance, acceptable du point de vue pharmaceutique, pour traiter la polyarthrite rhumatoïde. Cette invention a également trait à l'association du composé correspondant à la formule (I) ou d'un de ses sels acceptable du point de vue pharmaceutique avec un ou plusieurs médicaments modifiant l'évolution de la polyarthrite rhumatoïde.

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