Treatment of sexual dysfunction with non peptide bombesin...

A - Human Necessities – 61 – K

Patent

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A61K 31/165 (2006.01) A61K 31/17 (2006.01) A61K 31/18 (2006.01) A61K 31/196 (2006.01) A61K 31/395 (2006.01) A61K 31/4015 (2006.01) A61K 31/433 (2006.01) A61K 31/4412 (2006.01) A61K 31/454 (2006.01) A61K 45/06 (2006.01) A61P 15/10 (2006.01)

Patent

CA 2429106

Bombesin receptor antagonists have been found to be useful in the treatment of sexual dysfunction in both males and females. They may be selective BB1 antagonists or mixed BB1/BB2 antagonists. Combinations are disclosed of bombesin receptor antagonists with a range of other active compounds, for example PDE5 inhibitors, NEP inhibitors and lasofoxifene.

L'invention concerne des antagonistes du récepteur de la bombésine qui s'avèrent utiles pour traiter des dysfonctionnements sexuels chez l'homme comme chez la femme. Ces antagonistes peuvent être des antagonistes BB1 sélectifs ou des antagonistes BB1/BB2 mélangés. L'invention concerne également des combinaisons d'antagonistes du récepteur de la bombésine avec divers autres composés actifs, comme par exemple des inhibiteurs de PDE5, des inhibiteurs de NEP et le lasofoxifène.

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