Treatment of subnormal bone mineral density

A - Human Necessities – 61 – K

Patent

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Details

A61K 31/56 (2006.01) A61K 31/565 (2006.01) A61K 31/66 (2006.01) A61K 38/22 (2006.01) A61K 38/23 (2006.01) A61P 19/10 (2006.01)

Patent

CA 2390431

A method of treating an individual to increase the individual's bone mineral density (BMD) is disclosed. The method includes co-administering a calcitonin- like agent and a DHEA-like agent. Also disclosed are methods for potentiating the effect of treatment with a calcitonin-like agent on BMD and for increasing BMD in an individual being treated with DHEA, e.g., for treatment of systemic lupus erythematosus (SLE).

L'invention concerne une méthode de traitement d'un individu, visant à augmenter sa densité minérale osseuse (DMO). Le procédé consiste à co-administrer un agent du type calcitonine et un agent du type DHEA. L'invention concerne également des procédés permettant de potentialiser sur la DMO l'effet du traitement avec l'agent du type calcitonine, et d'augmenter la DMO chez un individu traité à la DHEA, p. ex. pour traiter le lupus érythémateux systémique (LES).

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