A - Human Necessities – 61 – K
Patent
A - Human Necessities
61
K
167/199
A61K 31/715 (2006.01)
Patent
CA 1094453
ABSTRACT OF THE DISCLOSURE It has been found that water-insoluble, thermogelable .beta.-1,3-glucan produced by microorganisms, lower polymers obtainable upon partial hydrolysis of the glucan or, carboxy- methylated derivatives of said glucan or of said lower polymers are useful for inhibiting growth of tumors in warm-blooded animals. The inhibitory activity against various tumors of these polysaccharides is very strong and significant whenever administered to warm-blooded animals from the early to very late stage of tumor progression or even when administered prior to plantation of tumors. The carboxymethylated derivatives above- mentioned are novel water-soluble compounds which can be pro- duced by carboxymethylation of said glucan and partial hydrolyzate thereof.
344027
Sasaki Takuma
Sugino Yukio
George H. Riches And Associates
Takeda Chemical Industries Ltd.
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