Treatment of upper airway allergic responses with a...

A - Human Necessities – 61 – K

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A61K 45/06 (2006.01)

Patent

CA 2263163

Relief from the symptoms of rhinitis is obtained by treatment with: (a) an antihistaminic effective amount of a histamine H1 receptor antagonist; together with (b) a sufficient amount of a histamine H3 receptor antagonist to provide a nasal decongestant effect. The components may be administered together in a single dosage form, or separately in the same or different dosage forms to maintain therapeutic systemic levels of both components.

On obtient un soulagement des symptômes de la rhinite à l'aide d'un traitement comprenant: (a) une dose efficace antihistaminique d'un antagoniste du récepteur H¿1? de l'histamine, de même que (b) une dose suffisante d'un antagoniste du récepteur H¿3? de l'histamine, afin de produire un effet décongestionnant nasal. On peut administrer ces composants ensemble, sous forme galénique unique, ou séparément dans la même forme galénique ou dans une forme différente, afin de maintenir les niveaux systémiques thérapeutiques de ces deux composants.

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