Treatment regimen utilizing neratinib for breast cancer

Details Treatment regimen utilizing neratinib for breast cancer Treatment regimen utilizing neratinib for breast cancer

A - Human Necessities

61

K

A61K 31/4709 (2006.01) A61P 35/00 (2006.01)

Patent

CA 2755789

An extended regimen for treatment of HER-2/neu overexpressed/amplified cancer is described, with involves de-livering a course of neratinib therapy to HER-2/neu overexpressed/amplified cancer patients following the completion of surgical and adjuvant therapy. The neratinib regimen may be continued for upwards of twelve months to five years. Also provided are pharmaceutical kits designed to facilitate compliance with the regimen.

L'invention porte sur un régime étendu pour le traitement d'un cancer dans lequel HER-2/neu est surexprimé/amplifié, qui met en jeu la distribution d'une cure de thérapie par nératinib chez des patients atteints d'un cancer dans lequel HER-2/neu est surexprimé/amplifié à la suite de l'achèvement d'une thérapie chirurgicale et par adjuvant. Le régime à base de nératinib peut être poursuivi pendant plus de douze mois jusqu'à cinq ans. L'invention porte également sur des coffrets pharmaceutiques conçus pour faciliter l'observance du régime.

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