A - Human Necessities – 61 – K
Patent
A - Human Necessities
61
K
A61K 31/519 (2006.01) A61K 31/00 (2006.01) A61K 31/40 (2006.01) A61K 31/402 (2006.01) A61K 31/4745 (2006.01) A61K 31/566 (2006.01) A61K 45/06 (2006.01) A61P 15/00 (2006.01)
Patent
CA 2398766
The present invention provides a method of treating female sexual dysfunction, the method comprising the step of administering to a patent, having or at risk of having one or more of the disorders or conditions associated with female sexual dysfunction, a therapeutically effective amount of a compound that attenuates the binding of agouti-related protein to melanocortin receptors, but does not attenuate the binding of .alpha.-melanocyte stimulating hormone to melanocortin receptors. The present invention also provides a method of identifying a compound that is useful for the treatment or prevention of female sexual dysfunction, the method comprising the steps of: 1) determining if a compound affects the binding of agouti-related protein to melanocortin receptors; 2) determining if a compound affects the binding of .alpha.- melanocyte stimulating hormone to melanocortin receptors; and 3) selecting a compound that attenuates the binding of agouti-related protein to melanocortin receptors, but does not affect the binding of .alpha.-melanocyte stimulating hormone to melanocortin receptors.
Carpino Philip Albert
Hadcock John Richard Neville
Pfizer Products Inc.
Smart & Biggar
LandOfFree
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