Tri(lower alkoxy) benzene derivatives

Details Tri(lower alkoxy) benzene derivatives Tri(lower alkoxy) benzene derivatives

C - Chemistry, Metallurgy

07

C

C07C 237/20 (2006.01) A61K 31/16 (2006.01) A61K 31/395 (2006.01) C07C 275/34 (2006.01) C07C 275/40 (2006.01) C07D 295/13 (2006.01) C07D 295/145 (2006.01) C07D 295/15 (2006.01)

Patent

CA 2094724

ABSTRACT OF THE DISCLOSURE This invention relates to a tri(lower alkoxy)ben- zene derivative of the general formula (I), or its salt, optical isomer or solvate, Image (I) wherein: R1, R2 and R3: same or different and each represents a lower alkyl group; A: a group of the formula Image or Image ; and R4 and R5: same or different and each represents a lower alkyl group, an aralkyl group or an aryl group, provided that R4 and R5 may, taken together with the adjacent nitrogen atom, form a pyrrolidinyl group, a piperid- ino group, a morpholino group, a thio- morpholino group, or a piperazinyl group optionally substituted by a lower alkyl group in 4-position; to pharmaceutical compositions containing the same, and to processes for their production. The compound of the - 45 - invention is useful as value as a pulmonary-surfactant secretion promoting agent. - 46 -

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