C - Chemistry – Metallurgy – 07 – D
Patent
C - Chemistry, Metallurgy
07
D
260/104
C07D 501/36 (2006.01) C07D 307/54 (2006.01) C07D 307/56 (2006.01) C07D 317/34 (2006.01) C07D 487/04 (2006.01)
Patent
CA 1142918
ABSTRACT The specification discloses a compound having the formula Image wherein A is Image or Image wherein R1 is hydrogen or formyl; R is or Image ; Image Y is hydrogen, chlorine, bromine, fluorine, trifluoro- methyl, amino, nitro, hydroxy, (lower)alkyl of 1-4 carbon atoms or (lower)alkoxy of 1-4 carbon atoms; R2 is (lower)alkyl of 1-4 carbon atoms and wherein A1 is methyl or -(CH2)nCOOH and n is one or two; or an easily hydrolyzed ester or nontoxic pharmaceutically acceptable salt thereof. There is also disclosed a process for the preparation of the compound, an easily hydrolyzed ester or nontoxic pharmaceutically acceptable salt thereof. The compound according to the present invention is effective in the treatment of bacterial infections in man.
282573
Iimura Seiji
Kamachi Hajime
Naito Takayuki
Okumura Jun
Bristol-Myers Squibb Company
Gowling Lafleur Henderson Llp
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