C - Chemistry – Metallurgy – 07 – D
Patent
C - Chemistry, Metallurgy
07
D
C07D 209/42 (2006.01) A61K 31/343 (2006.01) A61K 31/404 (2006.01) A61K 31/4439 (2006.01) A61P 3/06 (2006.01) C07D 307/85 (2006.01) C07D 401/12 (2006.01) C07D 401/14 (2006.01) C07D 403/12 (2006.01) C07D 405/12 (2006.01) C07D 409/12 (2006.01)
Patent
CA 2451474
The invention relates to triamide MTP/ApoB inhibitors of the formula 1, wherein R1-R8 are as defined in the specification, as well as pharmaceutical compositions and uses thereof, and processes for preparing the compounds. The compounds of the invention are useful for the treatment of obesity and lipid disorders.
L'invention relates porte sur des inhibiteurs de triamide MTP/ApoB de la formule (1) dans laquelle R<1>-R<8> sont tels que définis dans la demande, ainsi que sur des compositions pharmaceutiques et sur leurs utilisations, et sur des procédés de préparation des composés. Les composés de cette invention sont utiles dans le traitement de l'obésité et des troubles lipidiques.
Bertinato Peter
Blize Alan Elwood
Bronk Brian Scott
Cheng Hengmiao
Huatan Hiep
Pfizer Products Inc.
Smart & Biggar
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