C - Chemistry – Metallurgy – 07 – J
Patent
C - Chemistry, Metallurgy
07
J
260/19
C07J 43/00 (2006.01) C07J 11/00 (2006.01) C07J 13/00 (2006.01) C07J 41/00 (2006.01) C07J 71/00 (2006.01)
Patent
CA 1084484
ABSTRACT OF THE DISCLOSURE This invention relates to compounds of the general formula Image I wherein Ac is an alkylcarbonyl group containing 1 to 4 carbon atoms in the alkyl chain R is methylene or ? NR2 group - where R2 is a C1-3 alkyl, and all the three substituents R are of the same meaning n is 1 or 2 m is 1, 2, 3 or 4 and di-quaternary salts thereof of the general formula Image and tri-quaternary salts thereof of the general formula Image wherein Ac, R, n and m are given above R1 is C1-5 alkyl, or allyl and A is halogen, and pharmaceutically acceptable acid addition salts of the compounds of formula I. It also relates to a process for their preparation. The compounds of the invention exhibit a curone-like non-depolarizing neuromuscular-blocking effect.
258114
Biro Katalin
Karpati Egon
Marsai Maria
Szeberenyi Szabolcs
Szporny Laszlo
Fetherstonhaugh & Co.
Richter Gedeon Vegyeszeti Gyar Rt
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