Triaza-spiro compounds as nociceptin analogues and uses thereof

Details Triaza-spiro compounds as nociceptin analogues and uses thereof Triaza-spiro compounds as nociceptin analogues and uses thereof

C - Chemistry, Metallurgy

07

D

C07D 471/10 (2006.01) A61K 31/4747 (2006.01) A61P 7/10 (2006.01) A61P 25/00 (2006.01) C07D 221/00 (2006.01) C07D 235/00 (2006.01) C07D 519/00 (2006.01)

Patent

CA 2532059

The present invention. relates to nociceptin analogues represented by the following formula I: and uses thereof to modulate biological functions. In one aspect, the invention provides modified triaza-spiroo compounds that include at least one specialized chemical group that is bound to the compounds. The invention has a wide range of applications including providing a. new class of therapeutically useful aquaretics.

L'invention concerne des analogues de nociceptine et leurs utilisations pour moduler des fonctions biologiques. Dans un aspect, l'invention concerne des composés triazo-spiro modifiés comprenant au moins un groupe chimique spécialisé relié à ces composés. L'invention concerne une grande plage d'applications, notamment la fourniture d'une nouvelle classe d'aquarétiques thérapeutiquement efficaces.

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