Triazine compounds as pi3 kinase and mtor inhibitors

Details Triazine compounds as pi3 kinase and mtor inhibitors Triazine compounds as pi3 kinase and mtor inhibitors

C - Chemistry, Metallurgy

07

D

C07D 498/08 (2006.01) A61K 31/53 (2006.01) A61P 35/00 (2006.01)

Patent

CA 2721710

Compounds of formula (I) wherein: R1 is and R2, R4, and R6-9 are defined herein, and pharmaceutically acceptable salts and esters thereof. These compounds inhibit PI3 kinase and mTOR, and may be used to treat diseases mediated by PI3 kinase and mTOR, such as a variety of cancers. Methods for making and using the compounds of this invention are disclosed. Various compositions containing the compounds of this invention are also disclosed.

La présente invention concerne des composés de formule (I) dans laquelle : R1 est et R2, R4 et R6 à R9 sont définis aux présentes, et leurs sels et esters pharmaceutiquement acceptables. Ces composés inhibent la PI3-kinase et la mTOR et peuvent être utilisés pour traiter les maladies à médiation par la PI3-kinase et la mTOR, notamment toute une gamme de cancers. Linvention concerne des procédés de fabrication et dutilisation des composés ainsi que diverses compositions contenant les composés.

Affiliated with

Also associated with

Rating

Triazine compounds as pi3 kinase and mtor inhibitors does not yet have a rating. At this time, there are no reviews or comments for this patent.

If you have personal experience with Triazine compounds as pi3 kinase and mtor inhibitors, we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Triazine compounds as pi3 kinase and mtor inhibitors will most certainly appreciate the feedback.

Rate now

Comments { 0 }

Profile ID: LFCA-PAI-O-1704420