Triazole antifungal agents

C - Chemistry – Metallurgy – 07 – D

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C07D 249/08 (2006.01) A01N 43/653 (2006.01) A01N 43/713 (2006.01) C07C 45/00 (2006.01) C07D 257/04 (2006.01) C07D 403/06 (2006.01) C07D 521/00 (2006.01) C07F 7/18 (2006.01)

Patent

CA 1256110

ABSTRACT Compounds of the formula: Image --- (I) where R is phenyl optionally substituted by 1 to 3 substituents each independently selected from F, Cl, Br, I, trifluoromethyl, C1-C4 alkyl and C1-C4 alkoxy, or R is a 5-chloropyrid-2-yl group; and R1 is H, Cl, phenyl optionally substituted by 1 to 3 substituents each independently selected from F, Cl, Br, I and trifluoromethyl or a heterocyclic group linked by a carbon atom, and their salts are useful in the treatment of fungal infections in humans and animals and as agricultural fungicides.

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