Triazole compounds and the use thereof as dopamine-d3-ligands

Details Triazole compounds and the use thereof as dopamine-d3-ligands Triazole compounds and the use thereof as dopamine-d3-ligands

C - Chemistry, Metallurgy

07

D

C07D 249/12 (2006.01) A61K 31/33 (2006.01) A61K 31/41 (2006.01) C07D 249/08 (2006.01) C07D 401/12 (2006.01) C07D 401/14 (2006.01) C07D 403/12 (2006.01) C07D 403/14 (2006.01) C07D 405/14 (2006.01) C07D 409/14 (2006.01) C07D 413/14 (2006.01) C07D 417/14 (2006.01)

Patent

CA 2296102

The present invention relates to triazole compounds of formula (I), wherein Ar1, A, B and Ar2 have the meanings cited in the description. The inventive compounds exhibit high dopamine-D3-receptor affinity and can thus be used in the treatment of diseases responding to dopamine-D3-ligands.

La présente invention concerne des composés de triazole de la formule (I) dans laquelle Ar?1¿, A, B et Ar?2¿ ont les significations mentionnées dans la description. Ces composés présentent une affinité élevée pour le récepteur de la dopamine D¿3? et s'utilisent donc pour le traitement de maladies réagissant aux ligands de la dopamine D¿3?.

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