Triazole compounds as lipoxygenase inhibitors

Details Triazole compounds as lipoxygenase inhibitors Triazole compounds as lipoxygenase inhibitors

C - Chemistry, Metallurgy

07

D

C07D 249/04 (2006.01) A61K 31/4192 (2006.01) A61P 29/00 (2006.01) C07D 401/12 (2006.01) C07D 403/12 (2006.01) C07D 417/12 (2006.01)

Patent

CA 2627516

There is provided compounds of formula (I) wherein W is an optionally substituted aryl or heteroaryl group, and pharmaceutically-acceptable salts thereof, which compounds are useful in the treatment of diseases in which inhibition of the activity of a lipoxygenase (e.g. 15- lipoxygenase) is desired and/or required, and particularly in the treatment of inflammation.

L'invention concerne des composés représentés par la formule (I), dans laquelle W représente un aryle ou un groupe hétéroaryle éventuellement substitué, ainsi que des sels de qualité pharmaceutique de ceux-ci. Ces composés sont utilisés dans le traitement de certaines maladies dans lesquelles l'inhibition de l'activité de la lipoxygénase (par exemple, la lipoxygénase 15) est souhaitée et/ou nécessaire, et particulièrement dans le traitement de l'inflammation.

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