Triazole compounds that modulate hsp90 activity

Details Triazole compounds that modulate hsp90 activity Triazole compounds that modulate hsp90 activity

C - Chemistry, Metallurgy

07

D

C07D 249/08 (2006.01) A61K 31/4196 (2006.01) A61P 35/00 (2006.01) C07D 249/10 (2006.01) C07D 249/12 (2006.01) C07D 401/04 (2006.01) C07D 401/12 (2006.01) C07D 401/14 (2006.01) C07D 403/04 (2006.01) C07D 403/14 (2006.01) C07D 405/04 (2006.01) C07D 405/14 (2006.01) C07D 417/14 (2006.01)

Patent

CA 2677481

The present invention relates to substituted triazole compounds and compositions comprising substituted triazole compounds. The invention further relates to the use of a substituted triazole compound of the invention, or a composition comprising such a compound in the preparation of a medicament for preventing or treating hyperprolif erative disorders, such as cancer, in a subject in need thereof.

La présente invention concerne des composés à base de triazole substitué et des compositions comprenant des composés à base de triazole substitué. L'invention concerne, en outre, des procédés d'inhibition de l'activité de Hsp90 chez un sujet chez qui cela s'avère nécessaire, ainsi que des procédés de prévention ou de traitement d'affections impliquant une hyperprolifération, comme le cancer, chez un sujet chez qui cela s'avère nécessaire, comprenant l'administration au sujet d'un composé à base de triazole substitué de l'invention ou d'une composition comprenant ledit composé.

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