C - Chemistry – Metallurgy – 07 – D
Patent
C - Chemistry, Metallurgy
07
D
C07D 249/12 (2006.01) A61K 31/4196 (2006.01) A61P 35/00 (2006.01) C07D 401/04 (2006.01) C07D 401/14 (2006.01) C07D 403/04 (2006.01) C07D 405/04 (2006.01) C07D 405/14 (2006.01) C07D 413/14 (2006.01) C07D 487/04 (2006.01)
Patent
CA 2653329
The present invention relates to substituted triazole compounds and compositions comprising substituted triazole compounds. The invention further relates to methods of inhibiting the activity of Hsp90 in a subject in need thereof and methods for preventing or treating hyperproliferative disorders, such as cancer, in a subject in need thereof comprising administering to the subject a substituted triazole compound of the invention, or a composition comprising such a compound.
La présente invention concerne des composés de triazole substitué et des compositions comprenant ces composés de triazole substitué. L'invention concerne également des méthodes d'inhibition de l'activité de Hsp90 chez un sujet nécessitant un tel traitement et des méthodes de prévention ou de traitement de troubles hyperprolifératifs tels que le cancer chez un tel sujet, consistant à administrer à ce sujet un composé de triazole substitué de l'invention ou bien une compostion contenant un tel composé.
Chae Junghyun
Chimmanamada Dinesh U.
Demko Zachary
Du Zhenjian
Foley Kevin
Gowling Lafleur Henderson Llp
Synta Pharmaceuticals Corp.
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