C - Chemistry – Metallurgy – 07 – D
Patent
C - Chemistry, Metallurgy
07
D
C07D 249/12 (2006.01) A61K 31/4196 (2006.01) A61P 31/00 (2006.01) C07D 401/06 (2006.01) C07D 403/06 (2006.01) C07D 403/10 (2006.01) C07D 403/12 (2006.01) C07D 405/06 (2006.01) C07D 405/12 (2006.01)
Patent
CA 2653332
The present invention relates to substituted triazole compounds and compositions comprising substituted triazole compounds. The invention further relates to methods of inhibiting the activity of Hsp90 in a subject in need thereof and methods for preventing or treating hyperproliferative disorders, such as cancer, in a subject in need thereof comprising administering to the subject a substituted triazole compound of the invention, or a composition comprising such a compound.
La présente invention concerne des composés de triazole porteurs de substitutions et des compositions comprenant des composés de triazole porteurs de substitutions. L'invention concerne également des procédés qui permettent d'inhiber l'activité de la Hsp90 chez un sujet qui en a besoin, ainsi que des procédés de prévention ou de traitement d'affections hyperprolifératives telles que le cancer, chez un sujet qui en a besoin, par l'administration au sujet d'un composé de triazole porteur de substitutions selon l'invention ou d'une composition comprenant un tel composé.
Chimmanamada Dinesh U.
Du Zhenjian
Foley Kevin
Przewloka Teresa
Qin Shuzhen
Gowling Lafleur Henderson Llp
Synta Pharmaceuticals Corp.
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