C - Chemistry – Metallurgy – 07 – D
Patent
C - Chemistry, Metallurgy
07
D
C07D 249/12 (2006.01) A61K 31/4196 (2006.01) A61P 35/00 (2006.01) C07D 401/04 (2006.01) C07D 403/04 (2006.01) C07D 405/04 (2006.01)
Patent
CA 2586612
The present invention relates to substituted triazole compounds and compositions comprising substituted triazole compounds. The invention further relates to methods of inhibiting the activity of Hsp90 in a subject in need thereof and methods for preventing or treating hyperproliferative disorders, such as cancer, in a subject in need thereof comprising administering to the subject a substituted triazole compound of the invention, or a composition comprising such a compound.
La présente invention concerne des composés triazole substitués et des compositions renfermant lesdits composés. L'invention concerne également des méthodes propres à inhiber l'activité de Hsp90 chez un sujet qui en a besoin et des méthodes de prévention ou de traitement de troubles hyperprolifératifs, tels que le cancer, consistant à administrer au sujet qui en a besoin un composé triazole substitué de l'invention ou une composition renfermant un tel composé.
Barsoum James
Chae Junghyun
Chimmanamada Dinesh U.
Du Zhenjian
Foley Kevin
Gowling Lafleur Henderson Llp
Synta Pharmaceuticals Corp.
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