C - Chemistry – Metallurgy – 07 – K
Patent
C - Chemistry, Metallurgy
07
K
C07K 16/00 (2006.01) A61K 47/48 (2006.01) C07B 43/00 (2006.01) C07D 207/448 (2006.01) C07D 207/46 (2006.01) C07D 403/12 (2006.01) C07D 403/14 (2006.01) C07K 5/00 (2006.01) C08G 65/329 (2006.01)
Patent
CA 2617907
This invention relates to compounds comprising one or more therapeutic and/or diagnostic moieties and one or more functional moieties linked together via one or more triazole-containing linkers and to their intermediates and methods of their preparation. The triazole-containing linker may optionally contain one or more conditionally-cleavable or conditionally- transformable moieties and one or more spacer systems in between said moiety/moieties and the one or more therapeutic and/or diagnostic moieties.
L'invention concerne des composés contenant une ou plusieurs fractions thérapeutiques et/ou diagnostiques, et une ou plusieurs fractions fonctionnelles reliées par l'intermédiaire d'un ou de plusieurs bras de liaison contenant du triazole, ainsi que leurs intermédiaires, et des procédés permettant de les préparer. Le bras de liaison contenant du triazole peut contenir un ou plusieurs structures d'espaceurs entre la ou lesdites fractions, et la ou les fractions thérapeutiques et/ou diagnostiques.
Beusker Patrick Henry
de Groot Franciscus Marinus Hendrikus
Ridout & Maybee Llp
Syntarga B.v.
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