Triazole derivative

Details Triazole derivative Triazole derivative

C - Chemistry, Metallurgy

07

D

C07D 403/02 (2006.01) A61K 31/41 (2006.01) A61K 31/445 (2006.01) C07D 401/14 (2006.01) C07D 403/04 (2006.01) C07D 403/06 (2006.01) C07D 403/14 (2006.01) C07D 409/04 (2006.01) C07D 521/00 (2006.01)

Patent

CA 2060139

Triazole derivative, namely N,N-dimethyl-2-[5- (1,2,4-triazol-1-yl-methyl)-1H-indol-3-yl]ethylamine and its pharmaceutically acceptable salts are selective agonists of 5-HT1-like receptors and are therefore useful in the treatment of clinical conditions, in particular migraine and associated disorders, for which a selective agonist of these receptors is indicated. The triazole derivative is of formula: Image

Le dérivé du triazole, à savoir la N,N-diméthyl-2-¢5- (1,2,4-triazol-1-yl-méthyl)-1H-indol-3-yl!éthylamine, et ses sels de qualité pharmaceutique sont des agonistes sélectifs des récepteurs de type 5-HT1 et se révèlent donc utiles pour le traitement de problèmes cliniques, notamment de la migraine et de troubles connexes, où un agoniste sélectif est indiqué pour ces récepteurs. Le dérivé du triazole répond à la formule Image .

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