Triazole derivatives

Details Triazole derivatives Triazole derivatives

C - Chemistry, Metallurgy

07

D

C07D 249/08 (2006.01) A61K 31/41 (2006.01) A61K 31/4155 (2006.01) A61K 31/416 (2006.01) A61K 31/427 (2006.01) A61K 31/4439 (2006.01) A61K 31/4709 (2006.01) A61K 31/4725 (2006.01) A61K 31/517 (2006.01) A61K 31/5377 (2006.01) A61P 9/10 (2006.01) A61P 25/00 (2006.01) A61P 25/14 (2006.01) A61P 25/16 (2006.01) A61P 25/18 (2006.01) A61P 25/28 (2006.01) A61P 43/00 (2006.01) C07D 249/10 (2006.01) C07D 249/12 (2006.01) C07D 249/14 (2006.01) C07D 401/04 (2006.01) C07D 401/06 (2006.01) C07D 401/10 (2006.01) C07D 401/1

Patent

CA 2409819

The invention relates to a triazole derivative with an activity inhibiting glycine transporter and for use as a pharmaceutical drug, and a novel triazole derivative. The inventive triazole derivative has an excellent activity inhibiting glycine transporter and is useful as a therapeutic agent of dementia, schizophrenia, cognitive disorders, or cognitive disorders involved in various diseases such as Alzheimer disease, Parkinson's disease, or Huntington disease or the like, or spasm involved in diseases such as nerve degenerative diseases and cerebrovascular disorders, or the like. Particularly, the pharmaceutical drug is useful for the amelioration of learning disability of dementia and the like.

L'invention concerne des dérivés de triazole ayant une activité inhibitrice du transporteur de la glycine et utiles en tant que médicaments, ainsi que des nouveaux dérivés de triazole. En raison de leur excellente activité inhibitrice du transporteur de la glycine, lesdits dérivés de triazole sont utiles en tant que remèdes.

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