C - Chemistry – Metallurgy – 07 – D
Patent
C - Chemistry, Metallurgy
07
D
260/304.7, 167/9
C07D 407/06 (2006.01) C07C 45/63 (2006.01) C07D 249/08 (2006.01) C07D 317/16 (2006.01) C07D 521/00 (2006.01)
Patent
CA 1094079
JAB-169 TRIAZOLE DERIVATIVES ABSTRACT OF THE DISCLOSURE: Novel 1 -(.beta.-aryl)ethyl-1H-1, 2, 4-triazole ketals these compounds are of the formula: Image I or the therapeutically active acid addition salts thereof, wherein: Z is an alkylene consisting of -CH2-CH2-, -CH2-CH2-CH2-, -CH(CH3)-CH(CH3)- or -CH2-CH(alkyl)-, wherein said alkyl has from 1 to 10 carbon atoms; and Ar is phenyl, substituted phenyl, thienyl, halothienyl, naphthyl or 1uorenyl, and wherein "substituted phenyl" has the meaning of a phenyl radical having thereon from 1 to 3 substituents selected independently from the group consisting of halo, loweralkyl, loweralkyloxy, cyano or nitro. These compounds are valuable in the treatment of plants, animals and humans suffering from pathogenic micro-organisms.
239758
Heeres Jan
Van Reet Gustaaf
Wals Lourens
Gowling Lafleur Henderson Llp
Janssen Pharmaceutica Naamloze Vennootschap
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