Triazole derivatives and their production

C - Chemistry – Metallurgy – 07 – D

Patent

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Details

C07D 403/12 (2006.01) A61K 31/41 (2006.01) A61K 31/435 (2006.01) A61K 31/495 (2006.01) C07D 249/08 (2006.01) C07D 401/14 (2006.01) C07D 403/06 (2006.01) C07D 403/14 (2006.01) C07D 405/14 (2006.01) C07D 409/14 (2006.01) C07D 413/14 (2006.01) C07D 417/14 (2006.01) C07D 471/04 (2006.01) C07D 487/04 (2006.01) C07D 521/00 (2006.01)

Patent

CA 2239943

A compound of formula (I) or a salt thereof is useful as an intermediate for producing antifungal imidazolone or imidazolidinone with advantages from the industrial point of view. see fig (I) wherein Ar is a phenyl group which may be substituted; R1 is a hydrogen atom or lower alkyl: R2 is an aliphatic or aromatic hydrocarbon group which may be substituted or an aromatic heterocyclic group which may be substituted; R3 is a group of the formula -CH2Y (wherein Y is a hydroxyl group or a halogen atom) or a formyl group which may be protected.

Un composé de la formule (I) ou un sel correspondant est utile comme produit intermédiaire dans la production d'imidazole ou d'imidazolidinone antifongique comportant des avantages sur le plan industriel. Voir la figure (I) dans laquelle Ar est un groupement phényle qui peut être substitué; R1 est un atome d'hydrogène ou un alkyle léger; R2 est un groupement hydrocarboné aliphatique ou aromatique qui peut être substitué ou un groupement hétérocyclique aromatique qui peut être substitué; R3 est un groupement de formule -CH2Y (dans laquelle Y est un groupement hydroxyle ou un atome d'halogène) ou un groupement formyle qui peut être protégé.

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