Triazole derivatives for use as antimycotic agents

Details Triazole derivatives for use as antimycotic agents Triazole derivatives for use as antimycotic agents

C - Chemistry, Metallurgy

07

D

167/208, 260/313

C07D 249/08 (2006.01) A61K 31/41 (2006.01) C07D 401/12 (2006.01) C07D 521/00 (2006.01)

Patent

CA 1323877

Abstract of the disclosure Imidazole and triazole derivatives of the general formula Image (I) in which Ar denotes thienyl or denotes phenyl, biphenylyl or naphthyl, each of which is substituted by halogen, lower alkyl or lower alkoxy, R1 denotes hydrogen or lower alkyl, Alk denotes straight-chain or branched alkyl having 1 to 10 carbon atoms, Y denotes oxygen, sulfur, sulfinyl or sulfonyl, n denotes zero, 1 or 2, Z denotes oxygen, sulfur or sulfinyl, m denotes zero or 1, R3 denotes hydro- gen, straight-chain or branched alkyl, cyclohexyl, or de- notes phenyl which is optionally substituted by hydroxyl, halogen, trifluoromethyl, lower alkyl or lower alkoxy, or denotes biphenylyl, pyridyl or denotes naphthyl which is optionally substituted by halogen, X denotes CH or N, and R2 denotes hydrogen or lower alkyl, and their pharmaceu- tically acceptable acid addition salts for use as anti- mycotic agents in human and veterinary medicine.

554725

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