Triazole-derived kinase inhibitors and uses thereof

Details Triazole-derived kinase inhibitors and uses thereof Triazole-derived kinase inhibitors and uses thereof

C - Chemistry, Metallurgy

07

D

C07D 249/06 (2006.01) C07D 249/08 (2006.01) C07D 249/10 (2006.01) C07D 401/14 (2006.01) C07D 403/04 (2006.01) C07D 403/14 (2006.01) C07D 405/14 (2006.01) C07D 417/14 (2006.01) C07D 521/00 (2006.01)

Patent

CA 2445568

Described herein are compounds that are useful as protein kinase inhibitors having the formula: wherein Ht, R2, T, and m are as described in the specification. The compounds are useful for treating diseases in mammals that are alleviated by a protein kinase inhibitor, particularly diseases such as cancer, inflammatory disorders, restenosis, and cardiovascular disease.

La présente invention concerne des composés convenant comme inhibiteurs des protéines-kinases et représentés par la formule générale (I) dans Ht, R?2¿, T, et m sont conformes aux descriptions de la spécification. Ces composés conviennent pour le traitement d'affections touchant des mammifères, et se soignant au moyen d'un inhibiteur des protéines-kinases, et notamment les cancers, les troubles inflammatoires, la resténose, et des affections cardio-vasculaires.

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