Triazolo [1, 5-a] quinolines as adenosine a3 receptor ligands

Details Triazolo [1, 5-a] quinolines as adenosine a3 receptor ligands Triazolo [1, 5-a] quinolines as adenosine a3 receptor ligands

C - Chemistry, Metallurgy

07

D

C07D 471/04 (2006.01) A61K 31/4745 (2006.01) A61P 11/06 (2006.01) A61P 29/00 (2006.01) C07D 215/58 (2006.01) C07F 7/22 (2006.01)

Patent

CA 2689612

The present invention relates to the adenosine A3 receptor ligands of the general formula (I), within them favourably to the antagonists, to their salts, solvates, N-oxides and isomers, to the pharmaceutical compositions containing the compounds of the general formula (I), their salts, solvates, N-oxides and isomers, to the use of the compounds of the general formula (I), their salts, solvates, N-oxides and isomers, to the preparation of the compounds of the general formula (I), their salts, solvates, N-oxides and isomers, as well as to the new intermediates of the general formula (II), (VI), (XI), (XII) and (XV), and to the preparation thereof.

La présente invention porte sur les ligands du récepteur A3 de l'adénosine représentés par la formule générale (I), sur leurs antagonistes, sels, solvates, N-oxydes et isomères. Elle porte sur les compositions pharmaceutiques contenant les composés de formule générale (I), leurs sels, solvates, N-oxydes et isomères, sur l'utilisation des composés de formule générale (I), de leurs sels, solvates, N-oxydes et isomères, sur la préparation des composés de la formule générale (I), de leurs sels, solvates, N-oxydes et isomères, ainsi que sur les nouveaux intermédiaires des formules générales (II), (VI), (XI), (XII) et (XV), et sur leur préparation.

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