Triazolo [4,3-b] pyridazine derivatives and their uses for...

Details Triazolo [4,3-b] pyridazine derivatives and their uses for... Triazolo [4,3-b] pyridazine derivatives and their uses for...

C - Chemistry, Metallurgy

07

D

C07D 487/04 (2006.01) A61K 31/519 (2006.01) A61P 35/00 (2006.01)

Patent

CA 2749926

The invention concerns bicyclic compounds of Formula (I) wherein Formula (II), R1, R2, L1, L2, J, Y, k, n, p and r are as defined in the description. The present invention also relates to processes for the preparation of such compounds, pharmaceutical compositions containing them and their use in the treatment of androgen- receptor associated conditions, particularly prostate cancer.

La présente invention porte sur des composés bicycliques de formule (I) dans laquelle la formule (II), R1, R2, L1, L2, J, Y, k, n, p et r sont tels que définis dans la description. La présente invention porte également sur des procédés de préparation de tels composés, sur des compositions pharmaceutiques les contenant et sur leur utilisation pour le traitement d'affections associées aux récepteurs des androgènes, en particulier du cancer de la prostate.

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