Triazolo-pyridazine derivatives for the treatment of chronic...

Details Triazolo-pyridazine derivatives for the treatment of chronic... Triazolo-pyridazine derivatives for the treatment of chronic...

A - Human Necessities

61

K

A61K 31/50 (2006.01)

Patent

CA 2319426

The agent of the present invention can make an anti-asthmatic action, etc., of the triazolopyridazine derivatives [I] such as 6-(2,2-dimethyl-3-sulfamoyl-1- propoxy)-7-isopropyl[1,2,4]triazolo[1,5-b]pyridazine, etc., or salts thereof act on bronchi or tissues around bronchi specifically, and therefore, since local administering could be performed by a minimum effective amount of by the triazolopyridazine derivatives [I], it could avoid to administer an amount of the triazolopyridazine derivatives [I] into a whole body.

La présente invention concerne un agent pouvant avoir une action antiasthmatique, etc., cet agent renfermant des dérivés de triazolopyridazine [I] tels que 6-(2,2-diméthyl-3-sulfamoyl-1-propoxy)-7-isopropyl[1,2,4]triazolo[1,5-b]pyridazine, etc., ou des sels de celle-ci. Cet agent agissant spécifiquement sur les bronches ou sur les tissus entourant les bronches, on peut donc éviter d'administrer une quantité des dérivés de triazolopyridazine [I] dans le corps tout entier, pour procéder à une administration locale d'une quantité efficace minimale de ces dérivés de triazolopyridazine [I].

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