Triazolo-quinolin derivatives useful as adenosine receptor...

C - Chemistry – Metallurgy – 07 – D

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C07D 471/04 (2006.01) A61K 31/505 (2006.01) C07D 213/89 (2006.01) C07D 215/54 (2006.01) C07D 215/56 (2006.01) C07D 405/12 (2006.01)

Patent

CA 2470064

The present invention relates to adenosine A3 receptor ligands of the general formula (I), within those preferably antagonists, as well as their salts, solvates and isomers, and the pharmaceutical compositions containing them, to the use of the compounds of the general formula (I), as well as their salts, solvates and isomers, to the preparation of the compounds of the general formula (I) and theirs salts, solvates and isomers, furthermore to the new intermediates of the general formulae (II) and to the preparation thereof.

L'invention concerne des ligands récepteurs d'adénosine A<sb>3 </sb>représentés par la formule générale (I), de préférence, des antagonistes, ainsi que leurs sels, solvates et isomères, et des compositions pharmaceutiques les contenant. L'invention concerne également les composés de la formule générale (I), ainsi que leurs sels solvates et isomères, la préparation des composés de cette formule (I) et leurs sels solvates et isomères, ainsi que les nouveaux intermédiaires représentés par la formule (II) et leur préparation.

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