C - Chemistry – Metallurgy – 07 – D
Patent
C - Chemistry, Metallurgy
07
D
C07D 471/04 (2006.01) A61K 31/437 (2006.01) A61P 3/10 (2006.01) A61P 19/02 (2006.01)
Patent
CA 2701355
Novel compounds are provided which are 11 -beta-hydroxysteroid dehydrogenase type I inhibitors. 11 -beta-hy- droxysteroid dehydrogenase type I inhibitors are useful in treating, preventing, or slowing the progression of diseases requiring 11-beta-hydroxysteroid dehydrogenase type I inhibitor therapy. These novel compounds of formula I: or stereoisomers or pharma- ceutically acceptable salts thereof, wherein G, Q, X, Y, R3, R3a, and R3b are defined herein. Image
L'invention porte sur de nouveaux composés qui sont des inhibiteurs de la 11-bêta-hydroxystéroïde déhydrogénase de type I. Des inhibiteurs de 11-bêta-hydroxystéroïde déhydrogénase de type I sont utiles dans le traitement, la prévention ou le ralentissement de la progression de maladie nécessitant une thérapie par les inhibiteurs de 11-bêta-hydroxystéroïde déhydrogénase de type I. Ces nouveaux composés de formule I : ou stéréoisomères ou sels pharmaceutiquement acceptables de ceux-ci, dans lesquels G, Q, X, Y, R3, et R3b, sont définis présentement.
Cann Reginald O.
Deshpande Rajendra P.
Galella Michael
Kennedy Lawrence J.
Kolla Laxma R.
Bristol-Myers Squibb Company
Gowling Lafleur Henderson Llp
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