C - Chemistry – Metallurgy – 07 – D
Patent
C - Chemistry, Metallurgy
07
D
C07D 471/04 (2006.01)
Patent
CA 2642209
A compound of formula (Ia): or a pharmaceutically acceptable salt and/or solvate (including hydrate) thereof, or a compound of formula (Ib): or a pharmaceutically acceptable salt and/or solvate (including hydrate) thereof, and the use of a compound of formula (Ia) or (Ib) in the treatment of a TNF - mediated disease, disorder, or condition, or a p38 -mediated disease,. disorder, or condition, in particular the allergic and non-allergic airway diseases, more particularly obstructive or inflammatory airways diseases, preferably chronic obstructive pulmonary disease.
L'invention concerne un composé de formule (Ia), ou un sel et/ou solvate (y compris hydrate) pharmaceutiquement acceptable de ce composé, ou un composé de fomule (Ib), ou un sel et/ou solvate (y compris hydrate) pharmaceutiquement acceptable de ce composé, ainsi que l'utilisation d'un composé de formule (Ia) ou (Ib) pour le traitement d'une maladie, d'un trouble ou d'un état associé à l'activité du facteur de nécrose tumorale TNF, ou d'une maladie, d'un trouble ou d'un état associé à l'activité de la kinase p38, en particulier les maladies allergiques et non allergiques des voies respiratoires, plus particulièrement les maladies obstructives ou inflammatoires et de préférence la bronchopneumopathie obstructive chronique.
Lewthwaite Russell Andrew
Mathias John Paul
Phillips Christopher
Limited Pfizer
Smart & Biggar
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