Triazolopyridine compounds

Details Triazolopyridine compounds Triazolopyridine compounds

C - Chemistry, Metallurgy

07

D

C07D 471/04 (2006.01) A61K 31/437 (2006.01)

Patent

CA 2577478

This invention is directed generally to triazolopyridine compounds that generally inhibit p38 kinase, TNF, and/or cyclooxygenase activity. Such triazolopyridine include compounds generally corresponding in structure to the following formula (I): wherein R1, R2 and R3, are as defined in this specification. This invention also is directed to compositions of such triazolopyridines (particularly pharmaceutical compositions), intermediates for the syntheses of such triazolopyridines, methods for making such triazolopyridines, and methods for treating (including preventing) conditions (typically pathological conditions) associated with p38 kinase activity, TNF activity, and/or cyclooxygenase-2 activity.

Globalement, cette invention concerne des composés de triazolopyridine qui inhibent généralement l'activité de la kinase p38, de TNF, et/ou de la cyclooxygénase. Une telle triazolopyridine comprend des composés dont la structure correspond en général à la formule (I) suivante: Dans cette formule, R1, R2 et R3, sont comme définis dans le descriptif. L'invention concerne également des composition de telles triazolopyridines (en particulier des compositions pharmaceutiques), des intermédiaires convenant pour la synthèese de telles triazolopyridines, des procédés de fabrication desdites triazolopyridines, et des méthodes de traitement (et de prévention) de manifestations (généralement pathologiques) associées à l'activité de la kinase 38, à l'activité de TNF et/ou à l'activité de la cyclooxygénase-2.

Affiliated with

Also associated with

Rating

Triazolopyridine compounds does not yet have a rating. At this time, there are no reviews or comments for this patent.

If you have personal experience with Triazolopyridine compounds, we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Triazolopyridine compounds will most certainly appreciate the feedback.

Rate now

Comments { 0 }

Profile ID: LFCA-PAI-O-1843284