C - Chemistry – Metallurgy – 07 – D
Patent
C - Chemistry, Metallurgy
07
D
C07D 471/04 (2006.01) A61K 31/437 (2006.01) C07D 211/34 (2006.01) C07D 221/00 (2006.01) C07D 249/00 (2006.01) C07D 487/04 (2006.01)
Patent
CA 2338654
The invention is directed to novel triazolopyridine derivatives which are useful as antagonists of GPIIb/IIIa. Pharmaceutical compositions comprising the triazolopyridine derivatives of the present invention, methods of treating conditions mediated by GPIIb/IIIa (e.g., methods for treating platelet- mediated thrombotic disorders) along with processes for making the compounds and novel intermediates are also disclosed.
L'invention concerne de nouveaux dérivés de triazolopyridine utilisés comme antagonistes de GPIIb/IIIa. L'invention concerne également des compositions pharmaceutiques renfermant ces dérivés de triazolopyridine, des méthodes de traitement des états ayant pour origine GPIIb/IIIa (par exemple des méthodes destinées à traiter les dysfonctionnements thrombotiques d'origine plaquettaire), et enfin des processus de fabrication de composés et de nouveaux intermédiaires.
Hoekstra William J.
Lawson Edward C.
Maryanoff Bruce E.
Ogilvy Renault Llp/s.e.n.c.r.l.,s.r.l.
Ortho-Mcneil Pharmaceutical Inc.
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