Trichloro silyl alkyl isocyanate molecule and surface...

C - Chemistry – Metallurgy – 07 – F

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C07F 7/08 (2006.01) C40B 30/04 (2006.01) C40B 40/00 (2006.01) C40B 50/14 (2006.01) C40B 60/00 (2006.01) C40B 80/00 (2006.01) G01N 33/53 (2006.01)

Patent

CA 2589456

Molecule responding to formula X-E-SiCl3 wherein: X represents an isocyanate function -N=C=O and E represents an alkyl chain, its use for preparing a device comprising a mineral support (MS) and bound thereto a Self Assembled Monolayer (SAM) of molecules, the Self Assembled Monolayer grafted substrate thus obtained and its use in assays for detection of a target molecule and/or screening of interaction with other molecules.

La présente invention concerne une molécule représentée par la formule X-E-SiCl3 dans laquelle: X représente une fonction isocyanate -N=C=O et E représente une chaîne alkyle, son utilisation pour préparer un dispositif comprenant un support minéral (MS) et, liée à celui-ci, une monocouche auto assemblée (SAM) de molécules, le substrat greffé de monocouche auto assemblée ainsi obtenu et son utilisation dans des dosages de détection de molécule cible et/ou une recherche d'interaction avec d'autres molécules.

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