Tricyclic amides useful for inhibition of g-protein function...

C - Chemistry – Metallurgy – 07 – D

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C07D 401/14 (2006.01) A61K 31/445 (2006.01) A61K 31/495 (2006.01) C07D 401/12 (2006.01)

Patent

CA 2240846

Novel compounds, such as formulae (1.0), (4.0), (22.0), (27.0), (32.0) and (39.0) are disclosed. Also disclosed are methods for inhibiting the abnormal growth of cells, for inhibiting farnesyl protein transferase and for treating cancers using the novel compounds.

Nouveaux composés tels que ceux représentés par les formules (1.0), (4.0), (22.0) (27.0), (32.0) et (39.0), et procédés d'inhibition d'une croissance anormale des cellules, d'inhibition de la farnésyle protéine transférase et de traitement de cancers au moyen de ces nouveaux composés.

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