Tricyclic benzimidazoles and their use as metabotropic...

C - Chemistry – Metallurgy – 07 – D

Patent

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Details

C07D 471/06 (2006.01) A61K 31/437 (2006.01) A61P 25/00 (2006.01) C07D 487/06 (2006.01) C07D 498/06 (2006.01)

Patent

CA 2616020

The invention provides for a compound of formula (I) or a pharmaceutically acceptable salt thereof; wherein R1, R2, R3, A, B, D, m, n, x, andy are defined as described in the specification. The invention additionally provides a pharmaceutically composition comprising the compound of formula (I), together with a method of using the same to treat or prevent neurological and psychiatric disorders. The compounds are useful in therapy related to the treatment or prevention of mGluR2 receptor-mediated disorders.

L'invention concerne un composé de formule (I) ou un sel pharmaceutiquement acceptable de ce dernier, formule dans laquelle R1, R2, R3, A, B, D, m, n,x et y sont tels que définis dans la spécification. Cette invention concerne également une composition pharmaceutique comprenant le composé de formule (I) ainsi qu'une méthode d'utilisation de ladite composition pour traiter ou prévenir des troubles neurologiques et psychiatriques. Ces composés sont utiles en thérapie associée au traitement ou à la prévention de troubles médiés par le récepteur mGluR2.

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