Tricyclic cage compounds, and their production and use

C - Chemistry – Metallurgy – 07 – D

Patent

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260/361.1, 260/3

C07D 307/93 (2006.01) C07C 17/093 (2006.01) C07D 333/78 (2006.01) C07D 407/02 (2006.01)

Patent

CA 1162194

ABSTRACT A compound of the formula: Image wherein A1 is a single bond, a C2-C5 alkylene group or a C1- C5 alkylidene group, A2 is a C2-C3 alkylene group or a C1-C3 alkylidene group, A3 is a C2-C4 alkylene group or a C1-C4 alkylidene group, X is -O- or -SOn- (wherein n is an integer of 0 to 2), R1 is a hydrogen atom, a C1-C5 alkyl group, a C3-C5 alkenyl group and R2 is a hydrogen atom, a C1-C5 alkyl group, a C3-C5 alkenyl group, a C2-C5 alkanoyl group, a C2- C5 alkoxycarbonyl group, a benzyloxycarbonyl group, or when taken together with the adjacent nitrogen atom, R1 and R2 may form a five or six-membered heterocyclic group, which exhibits excellent antiviral activity with no or weak side effects or toxicities.

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