Tricyclic carbamate compounds useful for inhibition of...

C - Chemistry – Metallurgy – 07 – D

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C07D 401/14 (2006.01) A61K 31/4545 (2006.01) A61K 31/495 (2006.01) A61K 31/496 (2006.01) C07D 401/12 (2006.01)

Patent

CA 2216231

A method of inhibiting Ras function and therefore inhibiting cellular growth is disclosed. The method comprises the administration of a compound selected from (800.00), (801.00), (802.00), (803.00), (804.00), or (805.00). Compounds of structures (800.00) - X805.00) are novel compounds. (see formula I)

L'invention décrit une méthode pour inhiber la fonction Ras et donc inhiber la croissance anormale des cellules. La méthode consiste en l'administration d'un composé choisi parmi (800.00), (801.00), (802.00), (803.00), (804.00) ou (805.00). Les composés de structure (800.00) - (805.00) sont de nouveaux composés.

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